Monoclonal antibodies Essay Example | Topics and Well Written Essays - 2000 words

Monoclonal antibodies - Essay Example The fusion of myeloma cells together with mammalian spleen cells results to a hybrid cells that produces a high amount of the monoclonal antibodies. Out of this experiment, two types of cells are produced. One has the potential to grow continuously while the other has the ability to produce large amounts of monoclonal antibodies. Monoclonal antibodies are works better than convectional drugs since the antibody specifically targets the antigen and does not have negative health effects like the conventional drugs, which causes side effects after being used (Hsu, 1990, 34). If the amount of monoclonal antibodies becomes excess in the blood, it means that there is the presence of abnormal protein in the blood.   Screening of blood helps to identify these proteins through a process called protein electrophoresis. The plasma cells in the bone marrow are the main source of the production of monoclonal antibody abnormally.Monoclonal antibodies production  Hybridoma produces the monoclona l antibodies. Hybridoma cells can be made through fusing two cells so that the characteristics of two cells can be combined into one cell. One of the two cells should be myeloma, which is the tumor cell while the other should be the antibody-producing cell. The hybridoma produced in the laboratory has the ability to replicate faster than the normal cells that produces antibodies (Newcombe, 2007, 23). One common way in which the immune system of the humans fights diseases or presence.... pecifically targets the antigen and does not have negative health effects like the conventional drugs, which causes side effects after being used (Hsu, 1990, 34). If the amount of monoclonal antibodies becomes excess in the blood, it means that there is the presence of abnormal protein in the blood. Screening of blood helps to identify these proteins through a process called protein electrophoresis. The plasma cells in the bone marrow are the main source of the production of monoclonal antibody abnormally. Monoclonal antibodies production Hybridoma produces the monoclonal antibodies. Hybridoma cells can be made through fusing two cells so that the characteristics of two cells can be combined into one cell. One of the two cells should be myeloma, which is the tumor cell while the other should be the antibody-producing cell. The hybridoma produced in the laboratory has the ability to replicate faster than the normal cells that produces antibodies (Newcombe, 2007, 23). On the other hand , the tumor cells have potential to grow endlessly and at a higher rate than the normal cells. A specific monoclonal antibody that is originally produced by the B-lymphocyte is manufactured by the hybridoma cells. One common way in which the immune system of the humans fights diseases or presence of an antigen is through the production of large amounts of antibodies (Birch, Lennox, 2000, 30). These antibodies keep circulating throughout the body until they come across an antigen, which they will attach themselves on. As soon as they attach themselves, they alert the rest of the immune system to produce many of the antibodies to fight the specific antigen found. Monoclonal antibody can be produced in the laboratory and its effectiveness carries a higher percentage since it is designed for a